Poor progression-free survival

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August undefined, 2024

WebJan 5, 2024 · The authors used a meta-analytic approach to ascertain the correlation between OS and second progression-free survival (PFS-2) and compared that with first progression-free survival (PFS-1) as well as ORR in contemporary randomized controlled trials of advanced solid malignancies that used PFS-2 as a prespecified end point. 4 PFS … WebDec 1, 2024 · The 1-year overall survival and progression-free survival rates were 78.0% and 50.2%, respectively. Furthermore, we identified extramedullary disease, light chain multiple myeloma, and certain high-risk cytogenetic factors as important independent predictors of a poor prognosis in those receiving anti-BCMA CAR T-cell therapy.

P53 Is Involved in Sunitinib Resistance and Poor Progression-free ...

WebThe patients were divided into high and low sIL-2R groups based on the median of sIL-2R levels at pretreatment. Progression-free survival (PFS) and overall survival (OS) of patients in the high and low sIL-2R groups were compared. The Kaplan–Meier curves of PFS and OS were evaluated using the log-rank test. WebDisease-free survival This statistic is the percentage of patients who have no signs of cancer during a certain period of time after treatment. Other names for this statistic are … shanna white trinity county

Understanding Event-Free Survival (EFS) After Treatment

WebApr 7, 2024 · A Progression-free survival and B overall survival in DLBCL patients with low, medium, or high normalized levels of surface TREM2 on M-MDSCs. Normalized MFI changes of surface TREM2 on M-MDSCs being grouped into < 2%, 2–44%, and > 44%; cut-off values for normalized MFI changes of surface TREM2 determined by ROC analysis and AUC. WebImmunohistochemistry revealed 11 p53-positive cases among 53 patients with mRCC. Kaplan-Meier analysis showed that p53-positive cases tended to be associated with poor … WebFeb 27, 2012 · The last few years have seen an increase in the number of randomized controlled trials (RCTs) of new agents in metastatic solid tumors using progression-free … polyphyly and paraphyly

Risk Factors Associated with Durable Progression-Free Survival in ...

Progression-Free Survival: What Does It Mean for Psychological …

WebJun 23, 2014 · Conclusions. Progression-free survival is expectedly poor for patients with BRAF-mutated metastatic colorectal cancer.Despite the ascertainment bias present (with … WebOct 18, 2011 · Progression-free survival (PFS) is frequently used as a primary end point in oncology clinical trials. Employing PFS instead of overall survival as the primary outcome … polyphyodont wikipediaWebBy contrast, the progression-free survival at 3 years was higher than 90% and thus similar to unselected patients. Accordingly, addition of rituximab to improve the presumably poor progression-free survival did not show any efficacy over standard treatment with BEACOPP escalated followed by radiotherapy to PET-positive residual disease. shanna wiggins hatfield

"WebApr 9, 2024 · Overall survival (OS) and progression-free survival (PFS) were evaluated using the Kaplan–Meier method with a log-rank test. The cumulative incidence of locoregional … " - Poor progression-free survival

Poor progression-free survival

Liver Metastasis Is Associated with Poor Progression-Free …

WebMethods Forty-three nasopharyngeal carcinoma patients less than 19 years old were recruited between April 2010 and April 2016. All patients were treated with IMRT (total dose 61.2-76 Gy) combined with cisplatin based chemotherapy. The Kaplan-Meier test was used to calculate overall survival (OS) and progression-free survival (PFS). WebProgression-free survival refers to the time from randomisation or initiation of treatment to the occurrence of disease progression or death. Disease progression is defined by the Response Evaluation Criteria in Solid Tumors as an increase in the sum of maximum …

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WebNivolumab, an anti–programmed death 1 antibody, has been approved for the treatment of NSCLC. Although nivolumab improves overall survival (OS) more than docetaxel when … WebFeb 1, 2012 · In general, correlations between PFS and OS were poor to moderate regardless of the cut-off used. Download : Download high-res image (61KB) Download : Download …

WebMay 20, 2024 · Progression-free survival (PFS) and overall survival (OS) were determined by Kaplan–Meier method. The median OS and PFS after first-line treatment were 9.7 and 4.0 years, respectively. WebThe aim of the present study was to identify clusters of metabolic heterogeneity, using a large MRSI dataset, and determine which of these clusters are predictive of progression …

WebJan 1, 2024 · Kaplan-Meier analysis for progression-free survival according to CRP in (A) whole study population, (B) melanoma patients, (C) NSCLC patients and (D) GU cancer … WebNational Center for Biotechnology Information

WebMay 8, 2024 · Of note, 10% of the patients had PS 2 at baseline and those patients who developed treatment-related rash (79%) had significantly better progression-free survival (PFS) and OS, with a median OS of 14.3 months versus 4.2 months. Considering the limited data in poor PS patients from clinical trials, real-life data become useful in decision-making.

WebFeb 17, 2024 · Progression-free survival rate. This is the number of people who have been treated for cancer and either have no signs of cancer recurrence or who have cancer that … polyphyodont animalsWebNov 12, 2024 · Progression-free survival (PFS) was defined according to revised National Cancer Institute criteria. Imaging evaluation was performed on each patient at TT. TMTV, evaluated on 18 FDG-PET, and tumor bulk, measured on CT, were analyzed at TT, after the last bridging treatment, if any, and before starting the lymphodepletion therapy. shanna wicks lawyerWebProgression-free survival as a potential surrogate for overall survival in metastatic breast cancer Catherine Beauchemin,1 Dan Cooper,2 Marie-Ève Lapierre,1 Louise Yelle,3 Jean ... shanna whitleyWebSep 17, 2024 · We aim to analyze progression-free survival at 24 months (PFS24) and subsequent overall survival (OS) in a large-scale multicenter cohort of patients. 1790 patients were included from the China ... shanna williams facebookWebJun 1, 2024 · Disease-free survival (DFS) is a number that tells the chances of staying free of a disease or cancer after a particular treatment. 1 It is the percentage of individuals in the treatment group who are likely to be free of the signs and symptoms of a disease after a specified duration of time. Disease-free survival rates are an indication of how ... shanna whittWebAug 12, 2024 · Kaplan–Meier survival curves of progression-free survival for the training cohort and te sting cohort. 2.3. Univariate and Multivaria te Analyses Based on CPH Model shanna willie twitterWebThe timing for long-term follow-up was not prespecified and the analysis was descriptive in nature. Ibrutinib was superior to ofatumumab in difficult-to-treat patients with relapsed or refractory CLL or SLL, as measured by progression-free survival, overall survival, and response. 2. Byrd, et al. N Engl J Med. 2014;371 (3):213-223. shanna willis atlas residential